Endocrine Abstracts

Background: Follicles imaturation, as the hallmark of polycystic ovarian syndrome caused by prenatal androgen exposure, is suspected to be effected through expression changes of related genes. The aim of this study was to evaluate gene expression and promoter methylation of GATA6 and Follistatin (FST), two factors involved in follicle maturation, in adult female rats prenatally exposed to androgen excess by comparing them with non-treated rats.Material a...